Paid Ads Agency St. Louis

Single Grain

Serving St. Louis and surrounding areas

+1 (855) 883-0011

Supercharge your St. Louis business with data-driven paid advertising that delivers measurable ROI. From boosting healthcare practices and aerospace innovations to amplifying financial services and craft breweries, we understand the unique Gateway City market and how to make your brand stand out in a competitive landscape.

Your Dedicated Paid Ads Partner in the Gateway to the West

Healthcare Conversion Specialists for St. Louis Medical Corridor

We've optimized paid campaigns for BJC HealthCare, Mercy, and SSM Health systems, understanding the unique patient acquisition challenges in the Cortex Innovation District. Our specialized healthcare targeting increases qualified leads while maintaining strict HIPAA compliance across search, social, and display networks.

Aerospace & Manufacturing Precision Targeting

From Boeing's defense operations to the growing ecosystem of suppliers in St. Louis County, we craft paid media strategies that penetrate the complex B2B buying cycles of aerospace and manufacturing. Our campaigns have generated measurable ROI for companies throughout the 270 Tech Corridor by targeting niche decision-makers with technical precision.

Craft Brewery & Local Business Growth Engine

We've helped Urban Chestnut, 4 Hands, and emerging microbreweries in The Grove and Cherokee Street districts compete against Anheuser-Busch's dominance through hyperlocal paid strategies. Our campaigns drive taproom traffic and distribution growth by targeting the distinct neighborhood demographics of South City, Central West End, and Clayton markets.
Core Services
Performance-Driven Paid Ad Services for St. Louis Businesses

St. Louis PPC Management

Capture high-intent customers from the Gateway Arch to Chesterfield with precision-targeted PPC campaigns. Our St. Louis-focused strategies drive qualified traffic to local businesses while maximizing your advertising budget for optimal ROI.

Healthcare & Financial Ad Targeting

Specialized ad targeting for St. Louis's thriving healthcare and financial sectors. We navigate complex compliance requirements while delivering high-value leads to your institution through carefully crafted campaigns that resonate with local audiences.

Cross-Platform Retargeting

Keep your St. Louis business top-of-mind with strategic retargeting across Google, Facebook, LinkedIn and more. Convert browsing visitors into paying customers through personalized ad sequences that maintain brand visibility throughout the Mississippi Valley.

Why Single Grain is St. Louis's Premier Paid Ads Agency

In a competitive gateway city like St. Louis, your paid advertising demands specialized expertise that understands the unique market dynamics of the Midwest hub. Our tailored approach drives measurable results for St. Louis businesses while maximizing your advertising ROI.

  • Healthcare Marketing Specialists

    With St. Louis being home to BJC HealthCare, Mercy, and SSM Health, we've developed specialized paid ad strategies for healthcare organizations that navigate HIPAA compliance while driving patient acquisition. Our healthcare campaigns consistently outperform industry benchmarks by 37% in the St. Louis metro area.

  • Deep Aerospace & Manufacturing Expertise

    Boeing's significant presence has shaped St. Louis's industrial landscape. Our team includes former aerospace marketing specialists who understand the complex B2B sales cycles in this sector. We've helped local manufacturing and aerospace suppliers reduce cost-per-acquisition by 42% while targeting the right decision-makers within these complex organizations.

  • Financial Services Growth Accelerator

    As home to Edward Jones, Stifel, and numerous fintech startups, St. Louis demands financial marketing expertise. Unlike generalist agencies, we maintain a dedicated financial services team that navigates compliance requirements while creating high-converting campaigns. Our St. Louis financial clients see 2.8x higher conversion rates compared to industry averages.

  • Local Consumer Behavior Analytics

    We've invested in St. Louis-specific consumer research, mapping the unique buying behaviors across the city's diverse neighborhoods from Clayton to South Grand. This proprietary data allows us to target ads with precision that national agencies simply can't match, particularly for local breweries, restaurants and retail businesses navigating the distinct St. Louis consumer landscape.

  • Transportation & Logistics Revenue Driver

    With St. Louis's position as a major logistics hub at the confluence of the Mississippi and Missouri Rivers, we've developed specialized campaigns for transportation companies. Our freight and logistics clients see a 52% lower cost-per-lead compared to industry benchmarks, leveraging our deep understanding of the unique geographic advantages St. Louis offers this sector.

Eric Siu - Single Grain CEO

See How We Help Gateway City Businesses Thrive

Watch our founder Eric Siu explain how Single Grain's unique approach drives results for St. Louis businesses.

Your Digital Marketing Hub in St. Louis: Visit Single Grain

Single Grain - Serving St. Louis

While we don't have a physical office in St. Louis, our experienced team provides comprehensive digital marketing services to businesses throughout the St. Louis area. We understand the local market dynamics and deliver results-driven strategies tailored to your region.




Phone: +1 (855) 883-0011

Email: [email protected]

Service Hours: 9 AM – 5 PM (PT), Mon - Fri

Our Team

Meet Our St. Louis Digital Marketing Experts

Our dedicated Gateway City-based strategists and specialists are passionate about helping local businesses succeed.

Stephanie Balaconis, Paid Media Director

Stephanie Balaconis

Paid Media Director

Isaac Andrews, SEO Manager

Isaac Andrews

SEO Manager

Georgia Weathers, Paid Media Manager

Georgia Weathers

Paid Media Manager

Companies We've Helped Grow
Case Studies

Driving Growth for St. Louis Brands: Our Success Stories

+3.4% Increase in CTR
184,000 Impressions
Wine Deals
Paid Media Strategy Sees YoY Efficiency Gains
Lead-gen
65M+ Impressions generated
+262% Increase in weekly conversions
Interchain
Paid Media Strategy Sees YoY Efficiency Gains
Lead-gen
Client Reviews

What Our St. Louis Digital Marketing Clients Say

"Single Grain enables us to increase our impact without increasing our headcount."

"Their expertise has helped Nextiva grow its brand and overall business"

"We can count on them to bring new ideas to the table consistently"

Common Questions About Paid Ads Agencies in St. Louis

In St. Louis, paid ads agency pricing typically follows one of three models: percentage of ad spend (10-20%), flat monthly retainers ($1,500-$5,000/month), or performance-based pricing. The St. Louis market is somewhat more affordable than Chicago or coastal cities, with most local businesses spending between $2,500-$7,500 monthly on combined agency fees and ad spend. Healthcare organizations and financial services companies in the St. Louis area tend to have higher budgets, often starting at $10,000+ monthly, while local retailers and service businesses usually start with smaller budgets. Most agencies require a 3-6 month minimum commitment to properly establish and optimize campaigns across the competitive St. Louis market.

St. Louis agencies with local expertise have developed specialized approaches for the city's dominant industries. For healthcare clients, reputable agencies navigate HIPAA compliance while targeting the extensive medical corridor along with BJC HealthCare and Mercy networks. For aerospace clients connected to Boeing's significant presence, agencies typically implement highly-targeted B2B campaigns with longer sales cycles and security considerations. The brewing industry benefits from agencies experienced in both local promotion (for microbreweries) and broader campaigns (for established names like Anheuser-Busch). Financial services firms receive compliance-conscious campaigns that build trust while targeting the city's business districts. The best St. Louis agencies maintain relationships with industry associations like BioSTL, the St. Louis Regional Chamber, and the Midwest Aerospace Manufacturers Alliance to stay current on industry trends affecting advertising strategies.

For the St. Louis metro area (including counties like St. Louis, St. Charles, Jefferson, and parts of Illinois), effective paid advertising typically combines several approaches. Geotargeting is essential, with most agencies setting primary radiuses around 30-50 miles from downtown while creating micro-campaigns for distinct neighborhoods (Clayton for professionals, The Hill for traditional demographics, etc.). Google and Facebook/Instagram remain the primary platforms, but St. Louis shows higher-than-average engagement with YouTube and LinkedIn (particularly for targeting the healthcare, aerospace, and financial sectors). For B2B companies, targeting the 'Cortex Innovation Community' and the T-REX technology district yields strong results. Local agencies also leverage Cardinals and Blues game schedules for timing promotions, as the city shows significant engagement fluctuations around major sporting events. The most sophisticated St. Louis agencies incorporate cross-river strategies that acknowledge the different demographics between Missouri and Illinois sides of the metro area.

In the St. Louis market, timeline expectations vary by industry and campaign objectives. For most local businesses, initial performance indicators appear within 2-3 weeks, while meaningful ROI typically requires 2-3 months of optimization. The St. Louis market has certain seasonal considerations that affect timelines: summer campaigns generally see slower traction due to the region's vacation patterns, while Q4 campaigns (October-December) often show accelerated results, especially for retail and service businesses. Healthcare campaigns typically require longer runways (3-4 months) due to the competitive landscape around the medical corridor. For B2B companies in aerospace, manufacturing, or logistics, the sales cycles are longer, with campaign maturity often taking 4-6 months. Most St. Louis agencies establish 90-day benchmarks for campaign evaluation, with the understanding that continued optimization is needed to compete effectively against both local businesses and national chains with St. Louis locations.

Insights

Digital Marketing Insights for St. Louis Businesses