CRO service pricing in San Diego varies based on project scope and agency expertise. For small businesses, expect to invest $2,500-$5,000 monthly for basic optimization services. Mid-sized companies typically spend $5,000-$10,000 monthly for comprehensive programs. Enterprise-level businesses in San Diego's competitive sectors like biotech and tech often invest $10,000-$20,000+ monthly for advanced CRO strategies. Many San Diego agencies offer tiered pricing models with options for one-time audits ($1,500-$3,000), ongoing optimization, or performance-based pricing where fees are partially tied to conversion improvements. Given San Diego's higher cost of living compared to national averages, expect rates to reflect this premium market, though still lower than Los Angeles or San Francisco agencies.